Our new Clinical Cancer Research study applies landscape ecology to post-treatment pancreatic cancer, showing that residual tumor-stroma topology predicts recurrence. AI-enabled analysis of routine H&E slides identified fragmented, interface-rich microenvironments linked to shorter disease-free survival and immune exclusion, supporting spatial pathology as a framework for tumor ecosystem risk stratification.
Tumor Landscape Analysis Preprint
Our new study introduces the Tumor Landscape Analysis (TLA) pipeline, a novel framework applying ecological principles to tumor biology. By quantifying spatial organization and microenvironmental diversity, TLA offers powerful insights into tumor behavior, evolution, and treatment response. Explore how spatial ecology can reshape precision oncology in our latest work.